"Utilisation of Hydrogen Peroxide in the Treatment of Recurrent Bacterial
Vaginosis"
Cardone A.,
Zarcone R., Borrelli A., Di Cunzolo A., Tartaglia E.
Minerva
Ginecol.
December, 2003
Volume 55 (6)
Pages 483-492
PMID: 14676737 [PuMed - indexed for MEDLINE]
A quote from the following paper...
"The results clearly show that the use of hydrogen peroxide in vagina can eliminate
the main symptoms of bacterial vaginosis... Moreover, hydrogen peroxide facilitates the restoration of normal vaginal
bacterial flora in 100% of cses and normal acid pH in 98% of cases. Hydrogen peroxide represents a valid alternative
to conventional treatments for recurrent bacterial vaginosis, and associates the absence of collateral effects with low costs,
excellent tolerability and real therapeutic efficacy."
We have not yet been able to obtain this complete article. Currently, we only have the...
ABSTRACT
1st Obstetric and Gynecologic Clinic,
Department of Gynecology, Obstetrics and Neonatology, Second University of Naples, Naples, Italy.
[Article in English, Italian]
AIM: The authors have evaluated
the real efficacy of using hydrogen peroxide for previously treated recurrent bacterial vaginosis that is resistant to other
forms of treatment. METHODS: The study included 58 women aged between 18 and 42 years old. Vaginal irrigations with 30 ml
of hydrogen peroxide (3%) were prescribed in the evening for a week. The follow-up was carried out 3 months after the end
of treatment. RESULTS: The results clearly show that the use of hydrogen peroxide in vagina can eliminate the main symptoms
of bacterial vaginosis, and in particular the malodorous leucoxanthorrhea in 89% of cases at 3 months after the end of treatment,
a result that is comparable to that obtained using metronidazole or clindamycin as a vaginal cream. Moreover, hydrogen peroxide
facilitates the restoration of normal vaginal bacterial flora (represented by H202-producing lactobacillus) in 100% of cases
and normal acid pH (pH<4.5) in 98% of cases; it also fosters the disappearance of clue cells from vaginal smears and anaerobic
pathogenic flora from vaginal secretions in 100% of cases. The amine test became negative in 97.8% of cases. All results underwent
statistical analysis and were found to be statistically significant. CONCLUSION: Hydrogen peroxide represents a valid alternative
to conventional treatments for recurrent bacterial vaginosis, and associates the absence of collateral effects with low costs,
excellent tolerability and real therapeutic efficacy.