"Hydrogen Peroxide Release From Human Granulocytes During Phagocytosis"
R.K. Root, J. Metcalf, N. Oshiro, and B. Chance
Journal of Clinical Investigation
Volume 55 (5)
PMID: 1123431 [PubMed - indexed
A quote from the following paper...
supplied in an extracellular location, readily diffuses into granulocytes to stimulate intracellular metabolic events, indicating
that cellular membranes provide no parrier to diffusion of this substance. Thus, it seems evident that the release of
hydrogen peroxide from granulocytes during phagocytosis represents diffusion from an expanded intracellular pool of free hydrogen
peroxide that develops during particle ingestion. The amount released should depend upon and reflect the concentration
of free intracellular hydrogen peroxide."
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