"Hydrogen Peroxide Kills Staphylococcus Aureus By Reacting With Staphylococcal
Iron To Form Hydroxyl Radical"
John
E. Repine, Richard B. Fox and Elaine M. Berger
The
Journal of Biological Chemistry
July
25, 1981
Volume 256 Number 14
Pages 7094-7096
PMID: 6265438 [PubMed - indexed for MEDLINE]
A quote from the following paper...
"Addressing the hypothesis that iron in microorganisms facilitates bactericidal mechanisms
by reacting with hydrogen peroxide to form the more toxic hydroxyl radical, the results of the present investigation supported
this premise. Increasing the concentration of iron in Staphylococcus Aureus increased their susceptibility to killing by hydrogen
peroxide. Thus, while iron is an essential growth nutrient, it may also provide an 'Achilles heel' for Staphylococcus Aureus."
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